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目的:分析脐动脉血流监测在胎儿生长受限(FGR)中的临床意义。方法:对产前检查诊断为FGR的100例孕妇进行脐动脉血流监测。脐动脉血流正常组38例,异常组62例。两组均应用10%的葡萄糖500 ml+能量合剂、复方氨基酸静点,10天为1疗程,同时休息、左侧卧位、吸氧。监测各项FGR指标并进行对比分析,跟踪围生儿结局。结果:脐动脉血流正常组中显效36例(94.74%),有效1例(5.26%);异常组显效0例,有效24例(38.71%),两组比较差异有统计学意义(P<0.01);正常组发生新生儿窒息2例(5.26%),无死胎及新生儿死亡;异常组发生新生儿窒息14例(22.58%),死胎1例(1.16%),新生儿死亡3例(4.84%)。结论:对于FGR者应密切监测脐动脉血流变化,了解治疗效果,确定分娩时机,降低围生儿死亡率。
Objective: To analyze the clinical significance of umbilical artery blood flow monitoring in fetal growth restriction (FGR). Methods: Umbilical artery blood flow was monitored in 100 pregnant women diagnosed as FGR by prenatal examination. 38 cases of normal umbilical artery blood flow, abnormal group of 62 cases. Both groups were applied 10% glucose 500 ml + energy mixture, compound amino acid static point, 10 days for a course of treatment, while resting, left lateral decubitus, oxygen. Monitoring various FGR indicators and comparative analysis, tracking perinatal outcome. Results: 36 cases (94.74%) were effective in normal umbilical arterial blood flow group and 1 case (5.26%) effective in the normal umbilical artery blood flow. There were 0 cases in the abnormal group and 24 cases (38.71%) in the effective group, with significant difference between the two groups (P < 0.01). Neonatal asphyxia occurred in 2 cases (5.26%) in the normal group and no stillbirth and neonatal death occurred. Abnormal neonatal asphyxia occurred in 14 cases (22.58%), stillbirth occurred in 1 case (1.16%), neonatal death occurred in 3 cases 4.84%). Conclusion: The FGR should be closely monitored umbilical artery blood flow changes, to understand the therapeutic effect, determine the timing of childbirth, reduce perinatal mortality.