清道夫受体A广泛分布于巨噬细胞、血管平滑肌细胞和内皮细胞等细胞上 ,具有广泛的配体识别谱 ,在多种生理、病理过程中发挥作用 ,如参与宿主防御、凋亡细胞的吞噬、细胞粘附等 ,与动脉粥样硬化等疾病有关。本文对清道夫受体A的分子结构、基因表达调控和生物学功能等作一综述。 Scavenger receptor A is widely distributed on macrophages, vascular smooth muscle cells and endothelial cells and other cells, has a broad spectrum of ligand recognition, in a variety of physiological and pathological processes, such as participation in host defense, apoptotic cells Phagocytosis, cell adhesion, and other diseases related to atherosclerosis. This article reviewed the molecular structure, gene expression regulation and biological function of scavenger receptor A.