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在法医病理学鉴定工作中,由早期缺血性心肌病变及致死性心律失常引起的心源性猝死常常缺乏典型的病理组织学改变,如何准确、客观地诊断、查明死因是法医病理学亟待解决的问题。近来研究发现的一些心肌特异性指标对心源性猝死的诊断有很好的应用前景。本文介绍几种常见心肌特异性标志物的生化特点、实验室检验方法以及临床和法医学应用前景,以期为心源性猝死的法医病理学鉴定提供依据。
In the forensic pathology identification work, sudden ischemic cardiomyopathy and fatal arrhythmia caused by sudden cardiac death often lack of typical histopathological changes, how to accurately and objectively diagnose and identify the cause of death is forensic pathology urgent solved problem. Recent studies found that some of the myocardial specificity of the diagnosis of sudden cardiac death have a good prospect. This article describes the biochemical characteristics of several common cardiac markers, laboratory tests and clinical and forensic applications, in order to provide a basis for forensic pathology identification of sudden cardiac death.