我们有~3H-DHA为放射配基,测得寒冷暴露后大鼠肝细胞膜β受体变化。结果是大鼠寒冷暴露1～3天,肝细胞膜β受体迅速增加,亲和力呈下降趋势。寒冷暴露1～4周,β受体明显减少,亲和力则显著增强。所测得β受体主要是β受体。提示寒冷暴露β受体介导的NST,初期依赖于β受体数量变化,后期则是靠β受体质量更为有效而实现的。 We have ~ 3H-DHA as a radioligand, measured changes in rat liver cell membrane β receptors after cold exposure. The result is cold exposure of rats 1 to 3 days, liver cell membrane β receptor increased rapidly, the affinity showed a downward trend. Exposure to cold for 1 to 4 weeks, β receptor decreased significantly, the affinity was significantly enhanced. The measured beta receptors are mainly beta receptors. Tip cold exposed β receptor-mediated NST, initially depends on the number of β receptors, the latter depends on the β receptor mass more effectively achieved.