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目的比较血清补体3(C3)、高敏C反应蛋白(hsC-RP)与MS及其组分的相关性。方法纳入20岁以上的社区人群700名,测量身高、体重、WC、血压,测定C3、hsC-RP及血脂等。采用2005年IDF的MS诊断标准。结果 C3和hsC-RP水平随着MS组分数增加而升高,C3与各代谢指标的相关性均强于hsC-RP;高C3、高hsC-RP人群发生MS的风险均增加,OR值分别为3.97(P<0.01)和1.83(P<0.05)。结论 C3和hsC-RP均是MS的风险因子,其中C3对于MS的风险度高于hsC-RP。
Objective To compare the correlation between serum complement 3 (C3), high sensitivity C-reactive protein (hsC-RP) and MS and its components. Methods 700 community population over the age of 20 were included in the study. Height, weight, WC, blood pressure, C3, hsC-RP and blood lipids were measured. Adopt 2005 IDF MS diagnostic criteria. Results The levels of C3 and hsC-RP increased with the increase of MS group, and the correlation between C3 and each metabolic index was stronger than that of hsC-RP. The risk of MS in high C3 and high hsC-RP groups increased, 3.97 (P <0.01) and 1.83 (P <0.05). Conclusions Both C3 and hsC-RP are risk factors for MS, and the risk of C3 for MS is higher than that of hsC-RP.