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目的:分析中药联合血液透析治疗尿毒症性皮肤瘙痒(UP)的临床效果,为UP的治疗提供科学依据。方法:选取2014年2月至2016年1月在阳江市中医医院就诊的106例UP患者作为研究对象,根据治疗方式的不同分为观察组和对照组,各53例。对照组患者行血液透析治疗,观察组在此基础上采用自拟消风散加减内服进行治疗,研究不同治疗方法的效果。结果:观察组有效率为90.56%,对照组为69.81%,观察组高于对照组,差异具有统计学意义(P<0.05);治疗前,两组患者甲状旁腺激素(PTH)和β2微球蛋白(β2 MG)比较,差异无统计学意义(P>0.05),治疗后,观察组明显低于对照组,差异具有统计学意义(P<0.05)。结论:中药联合血液透析能有效缓解UP,具有较好的临床疗效。
Objective: To analyze the clinical effect of combined Chinese hemodialysis on uremic pruritus (UP) and provide a scientific basis for the treatment of UP. Methods: From February 2014 to January 2016, 106 cases of UP patients treated in Yangjiang Chinese Medicine Hospital were selected as the research object. According to the different treatment methods, the patients were divided into observation group and control group, with 53 cases in each group. Patients in the control group were treated with hemodialysis. On the basis of this, the observation group received self-made Xiaofeng San decoction for internal treatment and the effects of different treatment methods were studied. Results: The effective rate of the observation group was 90.56%, the control group was 69.81%, the observation group was higher than the control group, the difference was statistically significant (P <0.05); before treatment, the PTH and β2 Globulin (β2 MG), the difference was not statistically significant (P> 0.05), after treatment, the observation group was significantly lower than the control group, the difference was statistically significant (P <0.05). Conclusion: Traditional Chinese medicine combined hemodialysis can effectively relieve UP, has a good clinical efficacy.