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应用特异性单克隆抗体荧光偏振免疫法（ＭＡＦＰＩＡ）对６８例肾移植患者进行３６２次临床环孢素Ａ（ＣｓＡ）全血药物浓度监测。结果表明：合并用药会影响ＣｓＡ全血浓度。术后时间与ＣｓＡ全血浓度有一定关系。ＭＡＦＰＩＡ是一种简便、快速、准确的监测方法，对指导临床鉴别排异与中毒反应以及个体化给药，具有重要意义。
A total of 362 clinical CsA whole blood drug concentrations were monitored in 68 renal transplant recipients by using specific monoclonal antibody fluorescence polarization immunoassay (MAFPIA). The results show that: combination therapy will affect CsA whole blood concentration. Postoperative time and CsA whole blood concentration has a certain relationship. MAFPIA is a simple, rapid and accurate monitoring method. It is of great significance to guide the clinical identification of rejection and toxic reactions as well as individualized administration.