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作者探索了一种可认为是评价保护性软膏的有效方法,这种方法是在用软膏保护的、已被激起敏感的豚鼠皮肤上施用变应原。将豚鼠剪去脊部皮肤上的毛,用二硝基氟化苯(DNFB)(0.01M在乙醇、丙二醇中的溶液和在丙酮玉米油中的溶液),氨基苯甲酸乙酯5％溶于白石腊,月桂醇硫酸酯钠(5％水溶液),盐酸普鲁卡因(2％水溶液)和Oster油,试验其致敏感作用。在研究中,应用变应原以后约24小时,记录皮肤反应范围并作出评价。此外,用八种屏障软膏、乳膏和一种气溶胶作防护剂,评定对抗Ostet油对致敏豚鼠产
The authors explored an effective method of evaluating protective ointments by administering allergens to guinea pig skin that has been sensitized with an ointment and has been sensitized. Guinea pigs were cut off the hair on the ridged skin with 5% ethyl aminobenzoate dissolved in dinitrofluorobenzene (DNFB) (0.01 M solution in ethanol, propylene glycol and in acetone corn oil) White wax, sodium lauryl sulfate (5% aqueous solution), procaine hydrochloride (2% aqueous solution) and Oster oil were tested for their sensitization effects. In the study, about 24 hours after the application of the allergen, the skin reaction range was recorded and evaluated. In addition, eight barrier ointments, creams and an aerosol were used as protective agents to assess the efficacy of Ostet against sensitized guinea pigs