论文部分内容阅读
目的 建立中成药七宝美髯胶囊中有效成分补骨脂素和异补骨脂素的含量测定方法。方法 采用超临界流体萃取(SFE)技术和毛细管气相色谱(CGC)非在线联用技术测定补骨脂素和异补骨脂素的含量,HP-5毛细管柱,FID检测器,蒽为内标。结果 SFE-CGC法测定七宝美髯胶囊中补骨脂素和异补骨脂素简便快速,结果准确可靠,加样回收率分别为97,76％(RSD2.31％),101.21％(RSD2.12％)。结论 SFE-CGC法可以作为七宝美髯颗粒质量控制的方法之一。
Objective To establish a method for the determination of psoralen and isopsoralen, the active ingredients in Chinese traditional Chinese medicine Qibaomeiqi capsules. Methods The content of psoralen and isopsoralen were determined by using supercritical fluid extraction (SFE) and non-coupled capillary gas chromatography (CGC). The HP-5 capillary column, FID detector, and Xenon were used as internal standards. . Results SFE-CGC determination of psoralen and isopsoralen in Qibao Meiqi capsules was simple and rapid, and the results were accurate and reliable. The recoveries were 97.76% (RSD 2.31%) and 101.21% (RSD 2.12). %). Conclusion SFE-CGC method can be used as one of the methods for the quality control of Qibaomeiqi Particles.