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疟疾疫苗是防治疟疾的重要手段之一,采用基因工程技术构建重组疫苗正受到人们的关注。选择、建立适合疟原虫抗原基因表达的载体及其表达体系,对于研制和开发疟疾疫苗具有重大的意义。本文综述了近年来发展的可用于疟原虫抗原基因及亚单位疫苗的多种表达体系,介绍各种体系的
Malaria vaccine is one of the important measures to prevent and treat malaria, and the construction of recombinant vaccine by using genetic engineering is receiving more and more attention. The selection and establishment of a vector suitable for gene expression of the malaria antigen and its expression system are of great significance for the development and development of a malaria vaccine. This review summarizes the various expression systems available for plasmodium antigen genes and subunit vaccines developed in recent years,