胰岛移植或细胞治疗是根治1型糖尿病较为理想的方法,但同时也面临着供体匮乏的难题。近年来研究显示,除同种自体或异体胰岛外,异种胰岛尤其是选择猪供胰成为众多学者关注的焦点;另外对扩增胰腺β细胞及制造胰岛素分泌细胞株的研究亦取得了一定的成果;而干细胞工程及转基因技术的应用,使利用干细胞治疗糖尿病及人工构建类胰岛细胞成为可能。 Islet transplantation or cell therapy is the ideal method to cure type 1 diabetes, but it also faces the problem of donor deficiency. In recent years, studies have shown that in addition to the same kind of autologous or allogeneic islets, xeno-islets, especially pigs for the pancreas have become the focus of attention of many scholars; in addition to the expansion of pancreatic β cells and insulin-producing cell-producing research has also made some achievements ; And the application of stem cell engineering and transgenic technology makes it possible to use stem cells to treat diabetes and artificially construct islet cells.