【摘 要】
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IFITM5 (also known as BRIL) is a member of the interferon-induced transmembrane (IFITM) protein family.Unlike other IFITM members that are ubiquitously expresse
【机 构】
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Division in Anatomy and Developmental Biology, Department of Oral Biology, Oral Science Research Cen
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IFITM5 (also known as BRIL) is a member of the interferon-induced transmembrane (IFITM) protein family.Unlike other IFITM members that are ubiquitously expressed,IFITM5 is expressed specifically in osteoblasts and the expression peaks around initial stage of osteoblast mineralization [1].When IFITM5 is forcibly overexpressed,mineralization is enhanced,whereas silencing of IFITM5 expression inhibits mineralization.Furthermore,in the mouse embryo,IFITM5 expression is specific to particular elements of the skeletal system [1].
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