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目的:为了探索静脉注射胺碘酮(AM)治疗急性心肌梗死(AMI)合并室性心律失常的临床疗效和不良事件。方法:本组收治AMI合并室性心律失常120例。全部病例均在10 min内静脉注射AM 150 mg,无效者追加AM 150mg,随后静脉滴注维持,前6 h速度1 mg/min,后18 h速度0.5 mg/min。结果:有效87.50%(105例),无效10.83%(13例),死亡1.67%(2例),不良事件发生率25.83%(31例)。结论:AM治疗AMI合并室性心律失常安全、有效。
Objective: To explore the clinical efficacy and adverse events of intravenous amiodarone (AM) in the treatment of acute myocardial infarction (AMI) complicated with ventricular arrhythmia. Methods: The group received AMI combined ventricular arrhythmias in 120 cases. All patients were given AM 150 mg intravenously within 10 min and AM 150 mg ineffectively followed by IV infusion at 1 mg / min for the first 6 h and 0.5 mg / min after 18 h. Results: The effective rate was 87.50% (105 cases), invalid 10.83% (13 cases), death rate 1.67% (2 cases) and adverse event rate 25.83% (31 cases). Conclusion: AM is safe and effective in treating AMI with ventricular arrhythmia.