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小儿肺炎的过程不仅取决于病原体的特点和病变的范围,而且也取决于机体免疫系统的机能状态。据研究,肺脏病理和免疫缺陷相互联系互为因果。因此,研究肺炎患儿免疫状态对肺炎防治有重要意义。本文就近年有关文献作一综述。急性肺炎李氏报告113例中的普通型肺炎,细胞免疫功能(淋转率)无明显改变。研究呼吸道疾病确定肺炎急性期患儿细胞免疫功能低下,表现T 细胞减少,淋转率下降,白细胞吞噬活性降低。肺炎患儿体液免疫障碍表现为γ球蛋白失衡,李氏测得急性期 IgM 增高,其次为 IgG 增高,IgA 降低者较少,其余病例正常或增高。研究结果示肺炎患儿起病初期血清 IgG、M、A 明显增高。
The course of pediatric pneumonia depends not only on the characteristics of the pathogen and the extent of the lesion but also on the functional status of the body’s immune system. According to the study, lung pathology and immune defects are interdependent and causal. Therefore, to study the immune status of children with pneumonia prevention and treatment of pneumonia is of great significance. This article reviews recent literature. Acute pneumonia Lee reported 113 cases of common type of pneumonia, cellular immune function (no significant change in the rate of change). Study of respiratory diseases in children with acute lung disease identified cellular immune dysfunction, the performance of T cells decreased leaching rate decreased leukocyte phagocytic activity decreased. Humoral immunity in children with pneumonia showed gamma globulin imbalance, Lee measured acute increased IgM, followed by IgG increased, IgA decreased less, the rest of the normal or increased. The results showed that pneumonia early onset of serum IgG, M, A was significantly higher.