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何陇海同志[本刊2(4):55,1982]已对《临床药物手册》一书作了述评,本文除同意上述述评的观点外,本着爱护《手册》之衷,特补充提出以下几点意见,供作者再版时参考。1.16页四环素族的[副作用和毒性]项下,应补充以下几点内容:“(1)孕妇哺乳期的妇女和7岁以下儿童禁用四环素抗生素”,而且小儿用四环素已经淘汰。“(2)过期变质的四环素不可服用”.因为可引起一种综合症:恶心、呕吐、蛋白尿、酸中毒、糖尿、氨基酸尿等症状。“(3)金霉素由于性质不稳定,不良反应较多,除外用眼膏外,其它途径给药现已不用或很少应用”。
Comrade He Longhai [2 (4): 55, 1982] has commented on the Book of Clinical Pharmacology. In addition to agreeing with the above commentaries, this essay supplements the following in the spirit of protecting the “Handbook” Point of view for reference when reprinting the author. 1.16 Tetracycline [Side effects and toxicity] should be supplemented by the following: “(1) Pregnant women lactating women and children under the age of four disabled tetracycline antibiotics,” and children with tetracycline have been eliminated. “(2) Tetracycline expired can not be taken.” Because it can cause a syndrome: nausea, vomiting, proteinuria, acidosis, diabetes, amino aciduria and other symptoms. “(3) Chlortetracycline because of the nature of instability, more adverse reactions, except with ointment, other routes of administration is now or rarely used.”