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目的：观察小檗碱（黄连素）对短暂性脑缺血发作（ＴＩＡ）的临床疗效和对血小板聚集水平的影响。方法：口服小檗碱３００ｍｇ，每日３次，于服药前及服药后每隔１０天检测血小板聚集率１次，并设对照组口服羟乙基芦丁（维脑路通）２００ｍｇ，每日３次，对比临床疗效和血小板聚集率的变化。结果：小檗碱治疗３０天，血小板聚集率明显下降，ＴＩＡ发作频度明显降低。结论：小檗碱能降低ＴＩＡ患者血小板聚集率水平，缓解临床症状，是治疗ＴＩＡ、预防脑梗死的有效药物
Objective: To observe the clinical effect of berberine (berberine) on transient ischemic attack (TIA) and its effect on platelet aggregation. Methods: Berberine was orally administered 300 mg orally three times a day. The platelet aggregation rate was measured every 10 days before and after taking the medicine. The control group was given 200 mg of hydroxyethyl rutin (Venoruton) 3 times, comparing the clinical efficacy and changes in platelet aggregation rate. Results: Berberine treatment for 30 days, platelet aggregation decreased significantly, TIA seizure frequency was significantly lower. Conclusion: Berberine can reduce the level of platelet aggregation in patients with TIA and relieve clinical symptoms, and is an effective drug for the treatment of TIA and prevention of cerebral infarction