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目的探讨子前期-子患者并发脑血管疾病的临床和影像学特点。方法采用磁共振对2005年2月至2008年2月在天津医科大学总医院及武警医学院附属医院38例因出现脑病症状的子前期-子患者进行检查,根据检查结果分组,并对患者的临床症状、血压、肝肾功能、血常规、电解质等指标进行回顾性分析。结果磁共振检查异常的患者26例,24例为可复性后部脑病综合征,1例脑梗塞,1例颅内静脉窦血栓形成。磁共振检查异常组与磁共振检查正常组相比,血浆尿酸水平两组间比较差异有统计学意义(t=3.63,P=0.01),其余指标差异无统计学意义。结论磁共振检查显示子前期-子发生脑血管疾病绝大多数为后循环可复性脑病综合征。血尿酸水平可能在监测子前期-子患者发生脑血管疾病中有一定的应用价值。
Objective To investigate the clinical and imaging features of preeclampsia-subfamily patients with cerebrovascular disease. Methods Magnetic resonance imaging (MRI) was used to examine 38 cases of preeclampsia-subfamily of children with symptoms of encephalopathy at Tianjin Medical University General Hospital and Armed Police Medical College Affiliated Hospital from February 2005 to February 2008. The patients were grouped according to the examination results and Patients with clinical symptoms, blood pressure, liver and kidney function, blood, electrolytes and other indicators were retrospectively analyzed. RESULTS: Twenty-six patients with abnormal magnetic resonance imaging (MRI), 24 with recurrent encephalopathy syndrome, one with cerebral infarction, and one with intracranial venous sinus thrombosis. There was significant difference between the two groups in the level of plasma uric acid (t = 3.63, P = 0.01). There was no significant difference in other indexes between the two groups. Conclusions Magnetic resonance imaging showed that the majority of cerebrovascular diseases in preeclampsia-subfamily were retroperitoneal recurrent encephalopathy syndrome. Serum uric acid levels may have some value in the monitoring of preeclampsia - children with cerebrovascular disease.