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采用尿素酶法、ＰＣＲ法检测了８０例胃癌患者的幽门螺杆菌（ＨＰ）感染率，采用免疫组化ＡＢＣ法检测了其增殖细胞核抗原（ＰＣＮＡ）表达，并与对照组比较。结果显示，胃癌组的ＰＣＮＡ—ＬＩ表达明显高于对照组，ＨＰ感染阳性胃癌组的ＰＣＮＡ—ＬＩ表达高于阴性组，说明ＨＰ感染与胃癌的发生有密切关系，ＰＣＮＡ监测有助于胃癌的早期诊断
Urease method and PCR method were used to detect the Helicobacter pylori (HP) infection rate in 80 patients with gastric cancer. The expression of proliferating cell nuclear antigen (PCNA) was detected by immunohistochemical ABC method and compared with the control group. The results showed that the expression of PCNA-LI in gastric cancer group was significantly higher than that in the control group. The expression of PCNA-LI in the gastric cancer group with HP infection was higher than that in the negative group, indicating that HP infection is closely related to the occurrence of gastric cancer. PCNA monitoring is helpful for early gastric cancer. diagnosis