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目的探讨3.0T磁共振对比剂动态增强扫描量化参数在肝脏实性占位性病变鉴别诊断中的价值。方法利用3.0T磁共振对113个肝脏占位性病变进行对比剂动态增强扫描,分别测量各个病灶的动态增强曲线类型、最大上升斜率(MSI)、信号增强率(SER)、正性增强积分(PEI)、最大下降斜率(MSD)和峰值(PV),分析以上各参数在不同病变之间的差异。结果肝细胞癌(HCC)与除局灶性结节增生(FNH)外的各病,肝转移瘤与海绵状血管瘤、FNH及肝脓肿,FNH与海绵状血管瘤及肝脓肿之间强化曲线类型具有统计学差异(P<0.05)。海绵状血管瘤与其余各病,HCC与除FNH外的各病,FNH与肝转移瘤、肝内胆管细胞癌及肝脓肿,肝转移瘤与肝脓肿之间的MSI、PEI、MSD及PV存在统计学差异(P<0.05)。6种病变之间的SER未见统计学差异(P>0.05)。结论肝脏实性占位性病变的动态增强曲线类型和量化参数存在不同程度的差异,将两者结合有助于其鉴别诊断。
Objective To investigate the value of dynamic contrast-enhanced 3.0T magnetic resonance contrast-enhanced scan in the differential diagnosis of solid masses in liver. Methods Thirty-three liver lesions were contrast-enhanced with 3.0T magnetic resonance imaging. The dynamic enhancement curves, maximum rising slope (MSI), signal enhancement rate (SER) and positive enhancement score PEI), maximum descending slope (MSD) and peak (PV), and analyze the differences between the above parameters in different pathological changes. Results Intensive curve between hepatocellular carcinoma (HCC) and other diseases except focal nodular hyperplasia (FNH), liver metastases and cavernous hemangiomas, FNH and liver abscess, FNH and cavernous hemangiomas and liver abscess The type was statistically significant (P <0.05). Cavernous hemangiomas and other diseases, HCC and various diseases except FNH, presence of MSI, PEI, MSD and PV between FNH and liver metastases, intrahepatic cholangiocellular carcinoma and liver abscess, liver metastases and liver abscesses Statistical difference (P <0.05). There was no significant difference in SER between the 6 lesions (P> 0.05). Conclusion There are some differences between the dynamic enhancement curves and the quantitative parameters of liver solid space occupying lesions. The combination of the two can be helpful to the differential diagnosis.