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本文对3岁至15岁患变应性鼻炎及过敏性哮喘儿童92例进行了变应原脱敏治疗的疗效分组观察。疗效判定分为治疗后3月,半年,1年及1年半4个组,发现疗程越长脱敏治疗有效率越高,1年半组有效率高达94％,而就诊年龄7～9岁组有效率高于其他年龄组。脱敏治疗前后血清总IgE无统计学意义,鼻粘膜诱发试验治疗前后统计学处理存在显著差异(P<0.05),提示儿童脱敏治疗最适合的疗程为1年半,并以维持量持续治疗3～5年。疗效欠佳者亦应考虑多种变应原同时存在。
In this paper, 92 children aged 3 to 15 years suffering from allergic rhinitis and allergic asthma were treated with allergen desensitization treatment group observation. The curative effect was divided into 4 months after treatment, 6 months, 1 year and 1 year and a half after treatment. It was found that the longer the course of treatment, the higher the desensitization treatment efficiency, the effective rate was 94% in 1 year and a half, while the treatment age was 7 to 9 years Group efficiency than other age groups. The serum total IgE before and after desensitization treatment was not statistically significant. There was significant difference (P <0.05) between the nasal mucosal induction test before and after treatment, suggesting that the most suitable course of desensitization treatment for children was 1.5 years and maintained by continuous treatment 3 to 5 years. Poor efficacy should also consider the simultaneous presence of a variety of allergens.