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无远处转移的局部进展期胃癌,虽然有手术切除的机会,但与早期胃癌相比预后较差。局部晚期肿瘤不可切除率较高,且根治术后复发率较高。新辅助化疗对胃癌的治疗具有以下优点:减少肿瘤负荷,提高R0切除率,控制微转移,评价肿瘤对细胞毒药物的化疗敏感性。现介绍1例经天津医科大学附属肿瘤医院胃部肿瘤科治疗的进展期胃癌新辅助治疗病例,该患者经多学科协作诊疗后效果较好。通过报道该病例诊治以促进胃癌新辅助治疗经验交流,推动多学科间的合作。
Localized advanced gastric cancer without distant metastases, although with the opportunity of surgical resection, has a poorer prognosis than early gastric cancer. Localized unresectable tumor rate higher, and the recurrence rate after radical surgery higher. Neoadjuvant chemotherapy for gastric cancer treatment has the following advantages: reduce tumor burden, increase R0 resection rate, control micrometastasis, evaluate the tumor chemosensitivity to cytotoxic drugs. A case of advanced neoadjuvant treatment of advanced gastric cancer treated by Department of Stomach Tumors of Tumor Hospital Affiliated to Tianjin Medical University is presented. The result of this multidisciplinary collaboration is better. Through the report of diagnosis and treatment of this case to promote the neoadjuvant treatment of gastric cancer exchange of experiences and promote multidisciplinary cooperation.