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目的 探讨ⅢA期乳腺癌患者保乳手术的可行性和相关技术问题。方法结合相关文献回顾性分析3例ⅢA期乳腺癌保乳患者的临床特点和新辅助化疗后保乳手术的诊治经过。结果 新辅助化疗后3例患者的肿瘤和淋巴结均有明显缩小,其中1例获得了组织学上的完全缓解;术后无并发症;美容效果满意;分别随访40、20、11个月,至今尚未发现复发和转移的病例。结论部分ⅢA期乳腺癌在新辅助化疗后可以获得保乳机会,并有望获得和传统根治术相似的疗效。
Objective To investigate the feasibility and related technical problems of breast-conserving surgery in patients with stage ⅢA breast cancer. Methods The clinical features of breast-conserving patients with stage ⅢA breast cancer and the diagnosis and treatment of breast-conserving surgery after neo-adjuvant chemotherapy were retrospectively analyzed. Results After neoadjuvant chemotherapy, the tumors and lymph nodes were significantly reduced in 3 patients, of which 1 achieved histological complete remission; no postoperative complications; the cosmetic effect was satisfactory; and were followed up for 40, 20 and 11 months, respectively No cases of recurrence and metastasis have been found. Conclusions Part ⅢA breast cancer can obtain the chance of breast-conserving after neoadjuvant chemotherapy, and it is expected to obtain similar curative effect as traditional radical operation.