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众所周知,整合素αvβ3与肿瘤关系密切。以其作为抗肿瘤靶点的研究是现在的研究热点。同时,炎症靶向治疗和显影也越来越受到重视。研究发现,整合素αvβ3参与了炎症反应过程,包括炎症细胞趋化、浸润,炎症部位组织新生血管内皮形成等。这为将整合素αvβ3作为靶点开发炎症靶向治
As we all know, integrin αvβ3 and tumor closely. Its research as an anti-tumor target is now a hot research topic. At the same time, more and more attention has been paid to the targeted therapy and development of inflammation. The study found that integrin αvβ3 involved in the inflammatory reaction process, including inflammatory cell chemotaxis, infiltration, inflammatory tissue angiogenesis and other endothelial formation. This is a target for the development of integrin αvβ3 targeting the development of inflammation