一、前言乙胺碘呋酮广泛应用于临床已有十余年的历史。它的许多药理学特性至今尚未完全了解。每年国内外发表的大量文献主要集中在有关它的电生理学、血液动力学、药代动力学及临床应用等几方面。本文拟复习近年发表的资料,以供参考。二、历史概况乙胺碘呋酮于1961年合成后,开始用作扩冠药治疗心绞痛。1969年报道了它在动物的抗心律失常活性,1970年后陆续应用于临床。Rosenbaum于 I. Introduction Ethylamine iodine is widely used in clinical practice for more than ten years. Many of its pharmacological properties have not yet been fully understood. Each year a large number of published literatures mainly focus on its electrophysiology, hemodynamics, pharmacokinetics and clinical applications, and several other aspects. This article intends to review the information published in recent years for reference. Second, the historical profile Amiodarone in 1961 after the synthesis, began to expand the crown for the treatment of angina pectoris. It was reported in 1969 in animal anti-arrhythmic activity, after 1970, one after another applied to clinical. Rosenbaum at