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目的评价利多卡因混合肾上腺素骶管阻滞对全麻患儿血液动力学的影响。方法行腹部手术的患儿30例,随机分为3组(n=10):全麻组(Ⅰ组)、全麻加骶管阻滞(1%利多卡因8mg/kg)组(Ⅱ组)、全麻加骶管阻滞(1%利多卡因混合1∶200 000肾上腺素,8mg/kg)组(Ⅲ组)。分别于骶管阻滞前5min(T1)及骶管阻滞后5、10、15min(T2-4)时采用超声心动图仪监测心率、每搏量、心输出量,记录平均动脉压、收缩压、舒张压,计算全身血管阻力。结果与T1时比较,Ⅰ组T4时心率减慢,Ⅱ组T2-4时心率减慢,Ⅱ组T4时心输出量减少,Ⅲ组T4时舒张压降低(P<0.05);各组间血液动力学指标差异均无统计学意义(P>0.05)。结论单独应用利多卡因或混合肾上腺素行骶管阻滞对全麻患儿血液动力学无明显影响。
Objective To evaluate the effect of mixed adrenaline caudal block with lidocaine on hemodynamics in children under general anesthesia. Methods Thirty children with abdominal surgery were randomly divided into three groups (n = 10): general anesthesia group (group Ⅰ), general anesthesia plus caudal block (1% lidocaine 8 mg / kg) group (group Ⅱ ), General anesthesia plus caudal block (1% lidocaine mixed with 1: 200000 epinephrine, 8mg / kg) group (group Ⅲ). The heart rate, stroke volume and cardiac output were monitored by echocardiography at 5 min before sacral block (T1) and 5, 10 and 15 min after sacral block (T2-4) respectively. Mean arterial pressure Pressure, diastolic pressure, calculate systemic vascular resistance. Results Compared with T1, the heart rate of group Ⅰ slowed down at T4, the heart rate decreased at T2-4 of group Ⅱ, the cardiac output of group Ⅱ decreased at T4, and the diastolic blood pressure of group Ⅲ decreased at T4 (P <0.05) There was no significant difference in kinetic parameters (P> 0.05). Conclusions The caudal block of lidocaine alone or mixed adrenaline has no significant effect on the hemodynamics of general anesthesia children.