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报告了在米非司酮配伍口服米索前列醇基础上加肌注丙酸睾丸酮抗早孕的结果。绒毛出现明显的间质水肿、细胞坏变.微绒毛脱落、线粒体肿胀、粗面内质同扩张。完全流产率93.33%,较对照组高;6小时绒毛球排出率93.33%.完全流产后出血时间平均为8.61±2.15天,出血量估计为70.23±26.65ml,均较对照组(分别为73.33%、13.00±4.54天、95.19±40.41ml)有显著性差异。结果提示加用丙酸睾丸酮可加强米非司酮配伍米索前列醇抗早孕效果,促进绒毛球排出.缩短出血时间,减少出血量。该法使用方便.副反应轻,为目前国内药物抗早孕提供更安全、有效的配伍选择,有推广使用价值。
Reported in the combination of mifepristone oral misoprostol plus intramuscular injection of testosterone propionate anti-early pregnancy results. Fluffy obvious interstitial edema, cell degeneration. Microvilli shedding, mitochondria swelling, rough endoplasmic dilation. Complete abortion rate of 93.33%, higher than the control group; 6 hours villus discharge rate of 93.33%. The average bleeding time after complete abortion was 8.61 ± 2.15 days and the bleeding volume was estimated at 70.23 ± 26.65ml, which were significantly higher than those in the control group (73.33%, 13.00 ± 4.54 days, 95% .19 ± 40.41ml) were significantly different. The results suggest that the addition of testosterone propionate can enhance the anti-pregnancy effect of mifepristone and misoprostol to promote the villus discharge. Shorten the bleeding time, reduce the amount of bleeding. The method is easy to use. Side effects of light, for the current anti-pregnancy drugs to provide more secure, effective compatibility options, to promote the use of value.