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82岁男性,既往无血液系统疾病,入院时血小板在正常范围内。患者应用那屈肝素2 d,亚胺培南西司他丁钠6 d后,血小板降至66×10~9·L~(-1),考虑血小板减少症可能,停用那屈肝素。亚胺培南西司他丁停用换为头孢他啶。在入院第13天血小板降36×10~9·L~(-1)停可疑头孢他啶、氨溴索注射液,在加用利血生治疗后,血小板仍在急剧下降。在入院第20天血小板只有20×10~9·L~(-1)。考虑到药物因素仍不能除外,停用孟鲁司特钠。入院第34天血小板回升至57×10~9·L~(-1),患者一般情况良好,无特殊不适,体温正常,尿量色正常,予以出院。
82-year-old man with no previous blood-borne disease, with platelets admitted to the normal range. Patients with nadroparin 2 d, imipenem cilastatin sodium 6 d, the platelets dropped to 66 × 10 ~ 9 · L -1, considering the possibility of thrombocytopenia, disable nadroparin. Imipenem Cilastatin switched to ceftazidime. On the thirteenth day after admission, thrombocytopenia was stopped with suspicious ceftazidime and ambroxol injection at 36 × 10 ~ 9 · L ~ (-1). On the 20th day after admission, platelets only had 20 × 10 ~ 9 · L ~ (-1). Taking into account the drug factors can not be excluded, the discontinuation of montelukast sodium. On the 34th day after admission, the platelet returned to 57 × 10 ~ 9 · L ~ (-1). The patients were generally in good condition with no special discomfort, normal body temperature and normal urine output.