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目的:了解左氧氟沙星治疗社区获得性肺炎(CAP)的临床有效性和毒副作用。方法:调查我院2008年1月～2011年1月治疗的CAP患者72例,全部病例应用左氧氟沙星,每日一次0.4g静点,疗程为5～14天。结果:本组72例患者,有44例患者的痰培养检出多药耐药的肺炎链球菌,有16例患者检出铜绿假单胞菌,有12例患者检出流感嗜血杆菌,临床有效率为69%;细菌消除率为79%;临床表现为腹痛、丘疹、肾衰的各为2例,占16.7%。结论:应用左氧氟沙星治疗老年CAP具有疗效好、毒副作用相对较低的优点。
Objective: To understand the clinical efficacy and side effects of levofloxacin in the treatment of community-acquired pneumonia (CAP). Methods: A total of 72 CAP patients treated in our hospital from January 2008 to January 2011 were enrolled in this study. Levofloxacin was administered in all the patients, once daily for 0.4g. The course of treatment was 5 to 14 days. Results: The 72 patients in this group, 44 patients sputum culture detected multi-drug resistant Streptococcus pneumoniae, 16 patients were detected Pseudomonas aeruginosa, 12 patients were detected Haemophilus influenzae, clinical The effective rate was 69%; the bacterial elimination rate was 79%; the clinical manifestations were abdominal pain, papules and renal failure in 2 cases, accounting for 16.7%. Conclusion: The levofloxacin treatment of elderly CAP with good efficacy, the advantages of relatively low toxicity.