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为了在小白鼠先天性疟疾的研究中应用萤光抗体技术,从小白鼠及家兔制备了抗鼠疟原虫的血清。用铯~(137)炮作辐射源处理鼠疟原虫的红细胞期,每周一次,每次5,000伦,共7次,未能达到致弱疟原虫的目的。用作疫苗后,小白鼠发病死亡。一次照射30,000伦能杀死原虫,但连续接种11次后所得的血清,抗体活力很低。相反地,用感染的小白鼠血加肝
For the purpose of applying fluorescent antibody technology in the research of congenital malaria in mice, anti-Plasmodium sera were prepared from mice and rabbits. Erythrocytic stage of murine malaria parasite was treated with cesium-137 as a radiation source once a week for 5 times at a total of 7 times a day, failing to achieve the purpose of attenuating Plasmodium. After being used as a vaccine, the mice died of the disease. Once irradiated 30,000 Lun can kill protozoa, but after continuous inoculation of 11 times the serum obtained, antibody activity is low. Conversely, the liver is infected with infected white blood