目的探讨肿瘤相关物质(TSGF)水平与恶性肿瘤的相关性。方法采用癌症快速检测试剂盒测定恶性肿瘤患者血清中TSGF的浓度。结果多种恶性肿瘤患者血清TSGF明显增高;对于荷瘤的恶性肿瘤患者,化疗有效者,化疗后TSGF水平均明显下降,阳性率从治疗前的81.5%下降到51.4%。晚期肿瘤不能切除的患者与肿瘤根治术后患者血清TSGF相比较,根治术后的血清TSGF低于肿瘤不能切除的患者。结论 TSGF作为肿瘤检测标志物在肿瘤治疗中有一定的临床应用价值。 Objective To investigate the correlation between the level of tumor related substances (TSGF) and malignant tumors. Methods The concentration of TSGF in serum of patients with malignant tumor was determined by rapid detection kit of cancer. Results Serum TSGF levels were significantly increased in patients with various malignant tumors. For patients with malignant tumor, the levels of TSGF in patients with chemotherapy and chemotherapy were significantly decreased, and the positive rate decreased from 81.5% to 51.4% before treatment. Compared with TSGF in patients with advanced cancer who can not be removed, the serum TSGF after radical operation is lower than that in patients with unresectable tumor. Conclusion TSGF as a tumor marker in the treatment of cancer has some clinical value.