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目的分析肝炎肝硬化患者的肝功能检验结果 ,探讨肝炎与肝硬化关系。方法肝炎肝硬化患者94例纳入肝炎肝硬化组,Child-Pugh分级A级25例、B级30例、C级39例,分别纳入A、B、C亚组;取体检健康者50例纳入对照组,对比各组肝功能水平及肝炎肝硬化患者治疗前后肝功能水平。结果肝炎肝硬化组合计与A、B、C亚组血清胆固醇(CHO)、白蛋白(ALB)、血清胆碱酯酶(CHE)水平低于对照组,总胆汁酸(TBA)水平高于对照组,A亚组CHE、ALB、CHO水平高于B亚组、B亚组高于C亚组,A亚组TBA水平低于B亚组、B亚组低于C亚组,差异均具有统计学意义(P<0.05);治疗后肝炎肝硬化患者CHE、ALB、CHO水平高于治疗前,TBA水平低于治疗前,差异均具有统计学意义(P<0.05)。结论肝炎肝硬化患者的肝功能可预测Child-Pugh分级、评价疗效。
Objective To analyze the results of liver function tests in patients with liver cirrhosis and explore the relationship between hepatitis and cirrhosis. Methods Ninety-four patients with hepatitis cirrhosis were enrolled in the group of hepatitis cirrhosis, Child-Pugh grade A 25 cases, Grade B 30 cases, Grade C 39 cases were divided into A, B, C subgroups; 50 cases of healthy subjects were included in the control Group, comparing the level of liver function in each group and the level of liver function before and after treatment in patients with liver cirrhosis. Results The levels of serum total cholesterol (CHO), albumin (ALB) and serum cholinesterase (CHE) in patients with hepatitis and cirrhosis were lower than those in control group, and the levels of total bile acid (TBA) The levels of CHE, ALB and CHO in group A were higher than those in group B, while those in group B were higher than those in group C, while those in group A were lower than those in group B, while those in group B were lower than those in group C (P <0.05). The levels of CHE, ALB and CHO in patients with cirrhosis after treatment were higher than those before treatment and TBA was lower than before treatment (P <0.05). Conclusion The liver function of patients with cirrhosis can predict Child-Pugh classification and evaluate the curative effect.