胃肠道间质瘤(gastrointestinal stromal tumors,GIST)是一种较为少见的胃肠道非上皮源性的间充质肿瘤。由于其组织来源复杂,以往常被诊断为平滑肌瘤,平滑肌肉瘤或神经鞘瘤等。94%的GIST由于c-kit基因突变,导致酪氨酸激酶受体kit过度表达。因此,目前主要依靠其分子特点以及免疫 Gastrointestinal stromal tumors (GISTs) are a relatively rare non-epithelial mesenchymal tumor of the gastrointestinal tract. Due to its complex source of organization, previously diagnosed as leiomyoma, leiomyosarcoma or schwannoma and so on. 94% of GISTs are overexpressed by the tyrosine kinase receptor kit due to c-kit mutations. Therefore, at present mainly depends on its molecular characteristics and immunity