论文部分内容阅读
目的 探讨左旋咪唑所致脑病的CT、MRI表现。方法 回顾性分析临床确诊此病的6例病人的CT、MRI资料 ,其中 5例行钆喷替酸葡甲胺 (Gd DTPA)增强扫描 ,4例在MRI检查前行CT检查。结果 MRI表现 :共发现 6 4个病灶 ,主要位于双侧侧脑室周围及皮层下白质内 ,呈多发散在分布 ,大小不等 ;以不规则斑片 (块 )状最多 (36 / 6 4) ,其次为 (类 )圆形或小点状结节灶 ;病变T1WI多呈不均匀低信号 (5 7/ 6 4) ,T2 WI全部呈高信号 ,一般无强化 ;水肿及占位效应轻。液体衰减反转恢复序列(FLAIR)多呈明显高信号。CT表现 :2例表现为双侧侧脑室周围白质内多发散在分布的不规则斑片状低密度影 ;1例表现为双侧豆状核内对称性片状低密度影 ;另外 1例CT表现阴性。结论 CT、MRI对本病的诊断和鉴别诊断具有重要价值 ,MRI比CT具有更高的敏感性和特异性 ,能更好地评价其治疗和预后。
Objective To investigate the CT and MRI findings of levamisole-induced encephalopathy. Methods The CT and MRI data of 6 patients with clinically diagnosed disease were retrospectively analyzed. Among them, 5 patients underwent enhanced Gd DTPA scan and 4 patients underwent CT examination before MRI examination. Results MRI findings: A total of 64 lesions were found, mainly located in the bilateral lateral ventricles and subcortical white matter, and were mostly scattered and distributed in different sizes; with irregular patches (36/64) , Followed by (circular) or small nodular nodal lesions; lesions showed uneven T1WI low signal (57/64), T2 WI all showed high signal, generally no enhancement; edema and mass effect of light. Liquid attenuation inversion recovery sequence (FLAIR) showed significantly higher signal. CT manifestations: 2 cases showed irregular plaque-like low-density distribution in the white matter around the bilateral periventricular ventricle; 1 case showed symmetrical lamellar low-density shadow in the lentiform nucleus; the other 1 case of CT Negative performance. Conclusion CT and MRI have important value in the diagnosis and differential diagnosis of this disease. MRI is more sensitive and specific than CT, and can better evaluate its treatment and prognosis.