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目的探讨T2DM患者胸部CT表现及随访肺内病变变化与临床的关系。方法回顾性观察60例T2DM患者胸部CT图像,用CT视觉评分方法定量分析肺内病变,并与CT复查图像进行对照,分析肺内病变变化特征与临床的关系。结果 60例T2DM患者中胸部CT表现正常9例(15%)、磨玻璃样影31例(52%)、小叶间隔增厚32例(53%),多于胸膜下线8例(13%)、支气管血管束增厚3例(5%)、小叶内间质增厚3例(5%)等病变(χ2=76.979,P<0.01)。肺内病变具有周围分布、下肺分布为主的特点。复查后仅14例磨玻璃样病变有不同程度吸收,与磨玻璃影积分值无变化组相比,磨玻璃影积分值变化组病程较短(t=2.485,P=0.023),HbA1c较低(U=2.831,P=0.015)。结论 CT及其随访检查的半定量分析肺内病变,对评估糖尿病肺损害的短期变化及与临床的关系有一定价值。
Objective To investigate the clinical manifestations and clinical characteristics of chest CT in T2DM patients and their follow-up of lung lesions. Methods The CT images of 60 patients with T2DM were retrospectively reviewed. The pathological changes of the lungs were quantitatively analyzed by CT visual scoring method. The CT findings were compared with those of the CT images. The relationship between the characteristics of lung lesions and clinical features was analyzed. Results Sixty cases of T2DM showed normal CT findings in 9 cases (15%), ground glass - like lesions in 31 cases (52%), interlobular septal thickening in 32 cases (53%), more than in 8 cases (13% , Bronchovascular bundle thickening in 3 cases (5%), interstitial thickening in 3 cases (5%) and other lesions (χ2 = 76.979, P <0.01). Pulmonary lesions with the distribution around the lower lung-based features. After the review, only 14 cases of ground-glass-like lesions had different degrees of absorption. Compared with no changes in ground-glass integrals, ground-glass integral scores showed shorter duration (t = 2.485, P = 0.023) and lower HbA1c U = 2.831, P = 0.015). Conclusion CT and its follow-up semi-quantitative analysis of intrapulmonary lesions have some value in assessing the short-term changes of diabetic lung injury and their clinical relevance.