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目的研究小剂量尿激酶（ＵＫ）ＤＳＡ选择性动脉导管溶栓治疗急性脑梗塞的效果。方法选择急性脑梗塞住院病人６０例，随机分为动脉导管溶栓组（导管组）和静脉溶栓组（静脉组）各３０例，分别动脉导管注射和静脉注射小剂量ＵＫ１０～２０万Ｕ，于治疗前及治疗后１５天行临床神经功能缺损程度评分及脑ＣＴ检查作出疗效评价。结果导管组临床有效率９３．３３％，影像学有效率８０％，静脉组临床有效率７０％。两组有显著性差异（Ｐ＜０．０５）。结论小剂量ＵＫ选择性动脉导管溶栓在７２小时内治疗急性脑梗塞是一种安全有效的方法
Objective To investigate the effect of selective arterial catheter thrombolysis with low-dose urokinase (UK) DSA on acute cerebral infarction. Methods Sixty hospitalized patients with acute cerebral infarction were randomly divided into three groups: arterial catheter thrombolysis group (catheter group) and intravenous thrombolysis group (intravenous group), 30 patients were given arterial catheterization and intravenous injection of low dose of UK10 ~ 200000U, Before treatment and 15 days after treatment, the clinical neurological deficit score and brain CT examination were evaluated. Results The clinical effective rate of catheter group was 93.33%, the effective rate of imaging was 80% and the clinical efficiency of intravenous group was 70%. There was a significant difference between the two groups (P <0.05). Conclusions Small doses of UK-selective thrombolysis in the treatment of acute cerebral infarction within 72 hours is a safe and effective method