【摘 要】
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This study aimed to ascertain the current status of Japanese sperm banking for young cancer patients.During 2015,we mailed the directors of 695 institutes where sperm cryopreservation might be performed with questionnaires requesting information on the nu
【机 构】
：
Reproduction Center, Yokohama City University, Medical Center, Yokohama 232-0024, Japan;Department o
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This study aimed to ascertain the current status of Japanese sperm banking for young cancer patients.During 2015,we mailed the directors of 695 institutes where sperm cryopreservation might be performed with questionnaires requesting information on the number of patients,age,precryopreservation chemotherapy,semen analyses results and diagnoses,cryopreservation success rate,and causes of unsuccessful cryopreservation.Of these 695 institutes,92 had cryopreserved sperm before chemotherapy within the study period.In all,820 cancer patients (237 testicular,383 hematological,46 bone and soft tissue,20 brain,and 134 other malignancy) consulted the responding institutes for sperm cryopreservation.Except for testicular tumor,the number of patients whose sperm was preserved before cancer treatment was low compared to that of young cancer patients.Approximately 20％ of patients with malignancies other than testicular tumor underwent chemotherapy before cryopreservation.The success rate of cryopreservation in hematological malignancy was 82.5％,significantly lower than that of both the testicular cancer (93.6％) and other malignancy groups (95.6％) (P ＜ 0.05).The primary reasons for preservation failure were azoospermia and poor semen quality.Patients with hematological malignancies had a higher rate of unsuccessful cryopreservation compared to those in other groups,possibly due to the large number of patients requesting sperm cryopreservation after chemotherapy induction.In Japan,information regarding sperm banking prior to cancer treatment appears to be lacking.Information regarding sperm preservation before chemotherapy should be provided to all Japanese oncologists.
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