论文部分内容阅读
急性支气管痉挛通常采用β-受体兴奋剂如沙丁胺醇气雾剂治疗,但该类疾病也可采用抗胆碱能药如溴化异丙托品治疗。作者研究了单独采用沙丁胺醇或联合应用沙丁胺醇与溴化异丙托品对气喘和慢性阻塞性肺疾患(COPD)病人急性气流阻塞的作用。病例及方法 125例患急性气流阻塞的成年病人参加了试验,其中103例完成试验。病人随机给予单药10mg 沙丁胺醇气雾剂或联用10mg 沙丁胺酵气雾剂加0.5mg 溴化异丙托品。试验分为气喘组和 COPD组。气喘组66例,其中单用沙丁胺醇23例,平均年龄49岁,平均峰流速(PFR)145L/min;联合用
Acute bronchospasm is usually treated with beta-agonists such as salbutamol aerosol, but such disorders can also be treated with anticholinergics such as ipratropium bromide. The authors studied the effects of salbutamol alone or in combination with salbutamol and ipratropium bromide on acute airflow obstruction in asthmatic and chronic obstructive pulmonary disease (COPD) patients. Cases and Methods 125 adult patients with acute airflow obstruction participated in the trial, of which 103 completed the trial. Patients were randomized to receive either 10 mg salbutamol aerosol alone or 10 mg salbutamol aerosol plus 0.5 mg ipratropium bromide. The experiment was divided into asthma group and COPD group. Asthma group of 66 cases, including 23 cases of salbutamol alone, mean age 49 years, the average peak flow rate (PFR) 145L / min; combination