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目的 :验证氟罗沙星葡萄糖注射液对细菌性感染性疾病的疗效及其安全性。方法 :采用随机对照开放试验方法 ,选用氧氟沙星葡萄糖注射液作对照药。结果 :氟罗沙星葡萄糖注射液与氧氟沙星葡萄糖注射液的有效率分别为 87.9%与 74 % ,差异显著 (P <0 .0 1) ;两组患者细菌清除率为 88.8%和 85 .7% (P >0 .0 5 ) ;两组患者不良反应发生率分别为 15 .0 %和 16.0 % ,无显著差异 (P >0 .0 5 )。结论 :氟罗沙星葡萄糖注射液是一种广谱、有效、安全的抗菌药物。
Objective: To verify the efficacy and safety of fleroxacin and glucose injection in the treatment of bacterial infectious diseases. Methods: Randomized controlled open trial method, ofloxacin glucose injection as a reference drug. Results: The effective rates of fleroxacin dextrose injection and ofloxacin dextrose injection were 87.9% and 74%, respectively, with a significant difference (P <0.01). The bacterial clearance rates of the two groups were 88.8% and 85.7 % (P> 0.05). The incidence of adverse reactions in both groups was 15.0% and 16.0% respectively, with no significant difference (P> 0.05). Conclusion: Fleroxacin dextrose injection is a broad-spectrum, effective and safe antibacterial drug.