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目的观察卡前列甲酯栓联合葡萄糖酸钙预防宫缩乏力性产后出血的疗效。方法将110例足月妊娠产程过程中并发宫缩乏力的产妇随机分为对照组和观察组各55例,对照组于胎儿娩出后给予缩宫素20U静推并配合按压子宫,观察组于胎儿娩出后即刻直肠内放置卡前列甲酯栓,同时静脉推注10%葡萄糖酸钙10ml,观察两组治疗后疗效。结果观察组产后2h阴道出血量、24h出血量及第三产程时间均少于对照组,差异有统计学意义(P<0.05);两组用药前、后血压均无明显变化(P>0.05);观察组HB下降值显著低于对照组(P<0.05)。结论卡前列甲酯栓联合葡萄糖酸钙可有效缩短第三产程及减少产后出血量,是预防宫缩乏力性产后出血的理想药物,值得推广应用。
Objective To observe the curative effect of card tops methyl ester suppository combined with calcium gluconate in prevention of postpartum hemorrhage with uterine atony. Methods 110 cases of uterine atherosclerosis in the course of labor during pregnancy were randomly divided into control group and observation group, 55 cases in the control group after the delivery of the fetus given oxytocin 20U static push and press the uterus, the observation group in the fetus Immediately after delivery, put the card in the rectum methyl ester suppository, intravenous injection of 10% calcium gluconate 10ml, the two groups were observed after treatment. Results The amount of vaginal bleeding, 24h bleeding and the third stage of labor was less in the observation group than in the control group at 2 hours postpartum (P <0.05). There was no significant change in blood pressure before and after treatment in both groups (P> 0.05) ; HB in observation group was significantly lower than that in control group (P <0.05). Conclusions The combination of carbamazepine suppository and calcium gluconate can shorten the third stage of labor and reduce the amount of postpartum hemorrhage. It is an ideal drug to prevent postpartum hemorrhage due to uterine inertia. It is worth popularizing and applying.