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目的主要探讨慢性阻塞性肺疾病急性加重期(AECOPD)的短期全身性糖皮质激素治疗的疗效,并研究其对减轻AECOPD患者的经济负担方面的的影响。方法入选病例100例,短期糖皮质激素治疗组50例,在常规治疗基础上加用短期糖皮质激素治疗;对照组50例,只采用常规基础治疗。观察两组的临床症状、临床体征、肺功能、血气分析、住院天数、住院费用,并进行统计学分析。结果短期糖皮质激素组临床症状、临床体征、肺功能、血气分析改善及住院天数、住院费用方面差异有统计学意义(P<0.05)。结论短期全身性糖皮质激素治疗AECOPD能够达到改善预后和减轻患者经济负担的目的。
Objective To investigate the efficacy of short-term systemic glucocorticoid therapy in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) and to investigate its impact on reducing the financial burden of AECOPD patients. Methods 100 cases were enrolled in the study, 50 cases were treated with short-term glucocorticoid and 50 cases were treated with short-term glucocorticoid on the basis of routine treatment. Only 50 cases of control group were treated with routine basic treatment. The clinical symptoms, clinical signs, lung function, blood gas analysis, days of hospitalization, hospitalization expenses were observed and statistically analyzed. Results The clinical symptoms, clinical signs, lung function, improvement of blood gas analysis, days of hospitalization and hospitalization in the short-term glucocorticoid group were statistically significant (P <0.05). Conclusion Short-term systemic glucocorticoid therapy AECOPD can achieve the purpose of improving prognosis and reducing patients’ financial burden.