以３０例先天性心脏病肺动脉高压患者为对象，观察静脉注射卡托普利后血液动力学及激素的变化。结果表明，静脉注射卡托普利能快速降低肺动脉压力，改善血液动力学，同时抑制肾素系统活性，降低血浆心钠素水平。卡托普利能鉴别肺动脉高压的类型，也可作为术前降压的药物。 Thirty patients with congenital heart disease with pulmonary hypertension were enrolled in this study. The changes of hemodynamics and hormones were observed after intravenous injection of captopril. The results show that intravenous captopril can rapidly reduce pulmonary artery pressure, improve hemodynamics, while inhibiting renin activity, reduce plasma atrial natriuretic peptide levels. Captopril can identify the type of pulmonary hypertension, but also as a preoperative antihypertensive drugs.