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基质金属蛋白酶组织抑制剂在心血管疾病发生发展过程中的变化是近年来心血管领域研究的热点之一。现就基质金属蛋白酶抑制剂的分类和结构及在心肌重构、心力衰竭、心肌缺血再灌注损伤等的表达及作用作一综述。
Changes of matrix metalloproteinase inhibitor in the development of cardiovascular diseases in recent years one of the hot topics in cardiovascular research. Now on the classification and structure of matrix metalloproteinase inhibitors and myocardial remodeling, heart failure, myocardial ischemia-reperfusion injury expression and role are reviewed.