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支睾吸虫病(Clonorchiasis)是一种严重危害人类健康的常见寄生虫病,在中国、南朝鲜、日本和越南等国尤为多见。南朝鲜有200万人被感染,越南河内、海防地区的儿童和成人感染率分别为10%和40%,日本北方某些地区的感染率高达30～67%。(在我国有23个省市流行本病,流行区的感染率多数在5%以上,个别地区高达57%——译者注)长期以来,支睾吸虫病的防治进展不快,其原因之一乃缺乏有效的化疗药物。自1923年试用胂凡纳明以来的60多年中,先后研究和试用过多种药物。其中大多数因疗效不可靠,或
Clonorchiasis is a common parasitic disease that is seriously detrimental to human health and is particularly prevalent in countries such as China, South Korea, Japan and Vietnam. In South Korea, about 2 million people are infected. The prevalence of children and adults in Hanoi and Haiphong in Vietnam is 10% and 40%, respectively. In some parts of northern Japan, the infection rate is as high as 30% to 67%. (In our country, there are 23 provinces and cities prevalence of this disease, the prevalence of infection in most areas in more than 5%, in some areas up to 57% - Translator’s Note) For a long time, the progress of the prevention and treatment of clonorchiasis, one of the reasons Is the lack of effective chemotherapy drugs. In the 60 years since the trial of arsfannanamine in 1923, many kinds of drugs have been researched and tested successively. Most of them are unreliable due to their curative effect or