美国Hammerschmidt(1980)曾报告:摄食中国黑木耳能抑制血小板聚集,试管内试验亦证明黑木耳提取物能抑制血小板聚集,黑木耳中抑制血小板聚集的成分是水溶性的低分子量物质。最近,美国乔治·华盛顿大学的Makheja等将1体积中国黑木耳和20体积的磷酸盐缓冲液混合制成匀浆,经过离心后,获得一种提取物,他们研究此提取物对人的血小板聚集的影响。用此法处理,可从每克黑木耳中提取出400活性单位(1活性单位系指在1毫升富含血小板的血浆中,用3.2微克分子二磷酸腺苷引起的血小板聚集被抑制50%)。用有机溶媒处理后,其水溶性部分的活性仍大部分保存。在抑制血小板聚集的浓度,此提取物不影响[~(14)C]花 The United States Hammerschmidt (1980) has reported that ingestion of Chinese black fungus can inhibit platelet aggregation, and in vitro tests have also proved that black fungus extract can inhibit platelet aggregation. The components that inhibit platelet aggregation in black fungus are water-soluble low molecular weight substances. Recently, Makheja of George Washington University in the United States mixed one volume of Chinese black fungus with 20 volumes of phosphate buffer and homogenized. After centrifugation, an extract was obtained. They studied the platelet aggregation of this extract against humans. Impact. With this method, 400 active units can be extracted from each gram of black fungus (1 activity unit means that in platelet-rich plasma of 1 ml, a platelet aggregation caused by 3.2 μg of adenosine diphosphate is inhibited by 50%) . After treatment with organic solvents, the activity of the water-soluble fraction is still largely preserved. At concentrations that inhibit platelet aggregation, this extract does not affect [~(14)C]flowers