患儿男,5月龄,主因“发热3d,四肢出血性皮疹伴水肿、少尿1d”于2006-10-15入院。患儿入院前3d无明显诱因出现发热,当地医院给予静点林可霉素、病毒唑抗感染治疗。入院前1d患儿双下肢出现紫色皮疹,对称性分布。入院当天双下肢紫色皮疹进行性增多,面积增大、融合,并伴有双下肢的 Children male, 5 months old, mainly due to “fever 3d, extremity hemorrhagic rash with edema, oliguria 1d” in 2006-10-15 admission. There was no obvious predisposition to fever in children before admission, local hospitals were given intravenous lincomycin, ribavirin anti-infection treatment. A purple rash appeared on both lower extremities of children before admission, with symmetry distribution. On the day of admission, both lower extremities purple rash progressive increase in area, fusion, and accompanied by lower limbs