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目的探讨糖尿病患者尿清蛋白/尿肌酐(UALB/UCr)、α1微球蛋白(α1-MG)、视黄醇结合蛋白(RBP)和血胱抑素C(CysC)、C反应蛋白(CRP),糖化血红蛋白(HbA1c)对糖尿病肾病的诊断价值。方法采用免疫散射比浊法与免疫透射比浊法检测α1-MG、UALB/Ucr、Cys-C、RBP、CRP、HbA1c的水平。结果糖尿病肾病组显著高于健康对照组。结论联合检测UALB/Ucr、α1-MG、Cys-C、RBP、CRP、HbA1c可提高早期糖尿病肾病的诊断率。
Objective To investigate the relationship between urinary albumin / creatinine (UALB / UCr), α1-MG, RBP and CysC, CRP, , Glycosylated hemoglobin (HbA1c) in the diagnosis of diabetic nephropathy. Methods The levels of α1-MG, UALB / Ucr, Cys-C, RBP, CRP and HbA1c were detected by immune nephelometry and immunoturbidimetry. Results The diabetic nephropathy group was significantly higher than the healthy control group. Conclusion The combined detection of UALB / Ucr, α1-MG, Cys-C, RBP, CRP and HbA1c can improve the diagnosis rate of early diabetic nephropathy.