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目的探讨儿童糖皮质激素性高眼压症和青光眼的诊断、治疗及防治措施。方法回顾分析33例(42眼)儿童糖皮质激素性高眼压症和青光眼临床资料。结果所有患者停用糖皮质激素类药物,29眼(69.04%)眼压自行降至正常;13眼(30.95%)眼压不能自行恢复正常,其中10眼(23.80%)经过降眼压药物治疗后眼压恢复正常;另外3眼(7.14%)进行手术治疗。所有患者随访6~8个月,视力及眼压均稳定,视功能损害未进展。结论糖皮质激素类药物使用时疏于指导或滥用导致儿童糖皮质激素性高眼压症和青光眼发生,强调规范合理使用糖皮质激素类药物。
Objective To investigate the diagnosis, treatment and prevention and treatment of glucocorticoid-induced ocular hypertension and glaucoma in children. Methods A retrospective analysis of 33 cases (42 eyes) children with glucocorticoid-induced ocular hypertension and glaucoma clinical data. Results All patients discontinued glucocorticoid drugs. The intraocular pressure of 29 eyes (69.04%) went down to normal by themselves. The intraocular pressure of 13 eyes (30.95%) did not recover by themselves, and 10 eyes (23.80% IOP returned to normal; the other 3 eyes (7.14%) underwent surgical treatment. All patients were followed up for 6 to 8 months, visual acuity and intraocular pressure were stable, no impairment of visual function. Conclusion Glucocorticoids lead to glucocorticoid-induced ocular hypertension and glaucoma in children under the guidance or abuse, emphasizing the rational use of glucocorticoid drugs.