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目的:探讨小儿急性间质性肾炎的临床表现,病理,诊断,疗效及预后。方法:回顾性分析11例小儿急性间质性肾炎患儿的临床资料,其中症状较重的患者采用甲基泼尼松冲击后用泼尼松口服的方法进行治疗,症状较轻的仅需进行对症治疗,病情介于二者之间的可以口服泼尼松,如果有病情需要可以进行血透治疗。结果:治愈5例,45.45%,好转6例(54.55%),11例均有不同程度的肾功能损害。结论:小儿急性间质性肾炎临床表现不典型,早期诊断,早期综合治疗,可有效提高小儿急性间质性肾炎的治愈率。
Objective: To investigate the clinical manifestations, pathology, diagnosis, curative effect and prognosis of pediatric acute interstitial nephritis. Methods: The clinical data of 11 children with acute interstitial nephritis were retrospectively analyzed. The patients with severe symptoms were treated with methylprednisone after oral administration with prednisone, and the patients with mild symptoms were only treated Symptomatic treatment, the condition between the two can be oral prednisone, if there is a need for hemodialysis treatment. Results: 5 cases were cured, 45.45% were cured and 6 cases were improved (54.55%). All 11 cases had different degrees of renal dysfunction. Conclusion: The clinical manifestations of acute interstitial nephritis in children is not typical, early diagnosis, early comprehensive treatment, which can effectively improve the cure rate of children with acute interstitial nephritis.