骨髓纤维化(下简称骨纤)是骨髓增生综合征的一种。其突出表现为骨髓纤维组织明显增生,血中出现幼稚的粒、红细胞以及形态异常的红细胞,并有脾肿大及髓外造血。它有原发和继发之分。后者可继发于急性或慢性白血病,多发性骨髓瘤、何杰金氏病、前列腺癌、乳腺癌及接触放射性物质及毒物(如苯、氯等)。几年来,骨纤在世界各地均有陆续报告,我 Myelofibrosis (hereinafter referred to as bone fiber) is a kind of myeloproliferative syndrome. Its prominent manifestations of bone marrow fibrosis significantly hyperplasia, naive particles in the blood, red blood cells and abnormal red blood cells, and splenomegaly and extramedullary hematopoiesis. It has primary and secondary points. The latter can be secondary to acute or chronic leukemia, multiple myeloma, Hodgkin’s disease, prostate cancer, breast cancer and exposure to radioactive substances and poisons (such as benzene, chlorine, etc.). In recent years, bone fiber has been reported all over the world, I