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目的监测易县学龄儿童不同时期尿碘水平,观察不同干预措施的干预效果,为碘缺乏病防治工作提供科学依据。方法 1993—2012年间,每年在易县按东西南北中5个方位各随机抽取1个乡镇,每个乡镇随机抽取1所小学,每所小学随机抽取8~10岁儿童尿样20人份以上,采用尿碘砷铈催化分光光度法测定尿碘含量。结果随着补碘干预及碘盐干预基础上综合干预措施的实施,易县学龄儿童尿碘水平逐渐提高,并达到国家碘缺乏病消除标准,山区和平原儿童尿碘水平差异性逐渐消失。不同年龄、性别、民族儿童尿碘水平分布在各阶段差异均无统计学意义(P值均>0.05)。结论以碘盐干预为基础的综合干预措施可改善和提高学龄儿童碘营养水平,是防治碘缺乏病行之有效的方法,但应注意高碘摄入风险。
Objective To monitor urinary iodine levels of school-aged children in different ages and to observe the intervention effects of different interventions to provide a scientific basis for the prevention and treatment of iodine deficiency disorders. Methods Between 1993 and 2012, one township was randomly selected from each of the five orientations in east, west, north and south in Yixian County. One primary school was randomly selected in each township. Urine samples from 8 to 10 years old were randomly selected from each primary school for more than 20 samples. Urinary iodine arsenic cerium catalytic spectrophotometric determination of urinary iodine content. Results With the implementation of comprehensive interventions based on the intervention of iodine and iodized salt, the urinary iodine level of school-aged children in Yixian County gradually increased and reached the national standard of eliminating iodine deficiency disorders. The difference of urinary iodine level in children in mountainous and plain areas gradually disappeared. There was no significant difference in the distribution of urinary iodine among children of different ages, genders and ethnic groups (P> 0.05). Conclusion The comprehensive intervention based on iodized salt intervention can improve and enhance iodine nutrition in school-age children. It is an effective method to prevent and treat iodine deficiency disorders. However, the risk of high iodine intake should be paid attention to.